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Prostate cancer

How to understand your disease of aging: ageless man

Andropause disease with androgens stabilizes the prostate.

Ageless Man

Testosterone therapy in hypogonadal men does not increase the risk of prostate cancer

Androgens deprivation in prostate cancer is associated with a significant risk of Alzheimer's disease .pdf download

Androgen deprivation therapy (ADT) has been a mainstay of treatment of prostate cancer since the 1940s. Although its use has historically been limited to metastatic disease, randomized evidence supports the use of ADT in combination with external-beam radiation therapy for locoregional disease with high-risk features. Overall the use of ADT has increased dramatically over recent decades, with an estimated 500,000 men currently receiving ADT for prostate cancer in the United States. The side effects of this suppression of androgens may be significant: Androgen Deprivation Therapy and Future Alzheimer’s Disease Risk.pdf

 

PSA and Prostate cancer - errors to be avoided

Since years PSA test is used as a specific marker of prostate cancer (when PSA  also increases in adenoma or infection of the prostate).

PSA tests are also made to follow the treatments' responses.

The global mortality of prostate cancer has not been modified significantly since the beginning of twenty century.

In the USA they are insurers who do not refund any more detection of PSA tests for preventive diagnosis of the cancer of the prostate.

Notwithstanding, it would be interesting to know  PSA levels in each person at any age because the first stages of cell's  transformations and increase of PSA level can be reversed with appropriate therapy with androgens(exhaustive studies are necessary).

Many doctors have been slow to recognize that the use of PSA for screening lacks sensitivity and specificity, and cannot distinguish an aggressive from nonaggressive cancer, thereby leading to over-diagnosis and over-treatment (Richard J Ablin).  Download,pdf.

 Error 1:

PSA is not specific to prostate cancer. It is an activity's marker which level in the blood varies between 1 and 4 Nanograms/ml.

A simple prostate infection can elevate PSA levels. A prostate adenoma may also regress (prostate volume and PSA) with an appropriate therapy with androgens.

Error 2 :

To believe that testosterone provokes cancerous  prostate transformation ignoring the different grades of prostate cells.

They are ten grades to evaluate prostate cancer known as " Gleason's grades" :

 Error 3 :

To misunderstand the balance between testosterone and dihydrotestosterone on prostate cells.

Fatal Error 4  :

Misunderstanding  errors 1 to 3 and ignoring personalized therapy and companion diagnostics in each patient

 

 
 
History of andropause disease
Life maintenance system

A foundation of life maintenance system

Health in XXIst century
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