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 ANTI AGING SOLUTIONS FOR  WOMAN
 

 

 

ANDROGENS’ DEFICIENCIES BEFORE MENOPAUSE

 

  TEStosterone secretion decreases regularly from the age of 20 in woman:

The expected Testosterone concentration in the blood of a woman of 40 would be about half that of a woman of 21 (2).

ORAL CONTRACEPTIVE TROUBLES

Women using OCs (OC=Oral contraceptive) had significantly lower serum androgen levels compared to naturally cycling women and free testosterone levels displayed an inverse relation to breast epithelial proliferation (3.1).

OC use, however, has been associated with women's sexual health complaints and androgen insufficiency. OC use is associated with a decrease of androgen ovarian synthesis and an increase in the production of sex hormone-binding globulin (SHBG) even months after the stop of OC. Troubles may persist after stopping the OC(4).

 

CONSEQUENCES OF ORAL CONTRACEPTIVE TROUBLES WITH

Decrease of androgen ovarian synthesis

 

Thrombosis of the Deep Veins (3)

Hypertension (14/9) after 5 years of continuous use ( 5% of the cases) (3)

Pulmonary embolism  (risks x 2 to 12) .(3)

Disturbances of the plasmatic lipoproteins.(3)

Cerebral thromboembolism (risks x 3 to 9)        (3)

Resistance to insulin.(3)

Cerebral hemorrhage (risks x 2) (3)

 

Breast cancer risk

(3.1) (3.2) (3.3)

Sexual health complaints

(4)

 

BILATERAL OOPHORECTOMY

PREMENOPAUSE

In this condition balance between estradiol and progesterone could be impaired leading to fibromyoma of the uterus, spotting and bleeding. Androgen’s deficiency will be also considered in those cases.

Mesterolone therapy will benefit to all those cases with persisting troubles due to the decreased testosterone and dihydrotestosterone secretions.