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					TEStosterone 
					secretion decreases regularly from the age of 20 in woman: 
			
					
					 
					
					
					
					 
					
					
					The expected Testosterone concentration 
					
					in the blood of a woman of 40 would be about half that of a 
					woman of 21 (2). 
					
					
					 
			
					
					
					
					ORAL CONTRACEPTIVE TROUBLES 
					
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					Birth Control Guide of FDA 
					
					
					Women using OCs (OC=Oral contraceptive) had significantly 
					lower serum androgen levels compared to naturally cycling 
					women and free 
					testosterone levels displayed an inverse relation to
					breast 
					epithelial proliferation 
					(3.1). 
					
					
					OC 
					use, however, has been associated with women's sexual health 
					complaints and 
					androgen 
					insufficiency.
					OC use is 
					associated with a decrease of
					androgen 
					ovarian synthesis and an increase in the production of sex 
					hormone-binding globulin (SHBG) even months after the stop 
					of OC. Troubles may 
					persist after stopping the OC(4). 
					
						
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							CONSEQUENCES OF ORAL CONTRACEPTIVE TROUBLES WITH 
							
							
							
							
							Decrease of 
							androgen ovarian synthesis 
							
							
							
							
							  
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							Thrombosis of the Deep Veins (3) 
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							Hypertension (14/9) after 5 years of continuous use 
							( 5% of the cases) (3) 
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							Pulmonary embolism  (risks 
							x 2 to 12) .(3) 
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							Disturbances of the plasmatic lipoproteins.(3) 
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							Cerebral thromboembolism (risks x 3 to 9)       
							(3) 
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							Resistance to insulin.(3) 
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							Cerebral hemorrhage (risks x 2) (3) 
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							Breast cancer risk 
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							(3.1) (3.2) (3.3) 
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							Sexual health complaints 
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							(4) 
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					BILATERAL OOPHORECTOMY 
					 
			
			
			
					
					
					
					
					PREMENOPAUSE 
			 
								
			
					
					 
					
					
					In this condition balance between estradiol and progesterone 
					could be impaired leading to fibromyoma of the uterus, 
					spotting and bleeding. Androgen’s deficiency will be also 
					considered in those cases. 
					
					  
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